An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool.

Anderegg, Angela; Lin, Hsin-Pin; Chen, Jun-An; Caronia-Brown, Giuliana; Cherepanova, Natalya; Yun, Beth; Joksimovic, Milan; Rock, Jason; Harfe, Brian D; Johnson, Randy; Awatramani, Rajeshwar

Anderegg, Angela; Lin, Hsin-Pin; Chen, Jun-An; Caronia-Brown, Giuliana; Cherepanova, Natalya; Yun, Beth; Joksimovic, Milan; Rock, Jason; Harfe, Brian D; Johnson, Randy; Awatramani, Rajeshwar.

Afiliación

Anderegg A; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.
Lin HP; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.
Chen JA; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Caronia-Brown G; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.
Cherepanova N; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.
Yun B; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.
Joksimovic M; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.
Rock J; Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, United States of America.
Harfe BD; Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, United States of America.
Johnson R; Department of Biochemistry and Molecular Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America.
Awatramani R; Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America.

PLoS Genet ; 9(12): e1003973, 2013.

Article en En | MEDLINE | ID: mdl-24348261

Asunto(s)

Proteínas con Homeodominio LIM/genética; MicroARNs/metabolismo; Neurogénesis/genética; Enfermedad de Parkinson/genética; Factores de Transcripción/genética; Proteína Wnt1/genética; Animales; Diferenciación Celular/genética; ARN Helicasas DEAD-box/metabolismo; Dopamina/metabolismo; Neuronas Dopaminérgicas/citología; Neuronas Dopaminérgicas/metabolismo; Embrión de Mamíferos; Células Madre Embrionarias; Regulación del Desarrollo de la Expresión Génica; Humanos; Proteínas con Homeodominio LIM/metabolismo; Mesencéfalo/crecimiento & desarrollo; Mesencéfalo/metabolismo; Ratones; MicroARNs/genética; Enfermedad de Parkinson/metabolismo; Enfermedad de Parkinson/patología; Ribonucleasa III/metabolismo; Factores de Transcripción/metabolismo; Vía de Señalización Wnt/genética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Factores de Transcripción / MicroARNs / Proteína Wnt1 / Neurogénesis / Proteínas con Homeodominio LIM Límite: Animals / Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2013 Tipo del documento: Article País de afiliación: Estados Unidos

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