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Computationally designed liver-specific transcriptional modules and hyperactive factor IX improve hepatic gene therapy.
Nair, Nisha; Rincon, Melvin Y; Evens, Hanneke; Sarcar, Shilpita; Dastidar, Sumitava; Samara-Kuko, Emira; Ghandeharian, Omid; Man Viecelli, Hiu; Thöny, Beat; De Bleser, Pieter; VandenDriessche, Thierry; Chuah, Marinee K.
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  • Nair N; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium;
  • Rincon MY; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium; Center for Molecular and Vascular Biology, Department of Cardiovascular Medicine, University of Leuven, Leuven, Belgium;
  • Evens H; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium;
  • Sarcar S; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium;
  • Dastidar S; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium;
  • Samara-Kuko E; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium;
  • Ghandeharian O; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium;
  • Man Viecelli H; Department of Pediatrics, Division of Metabolism, University of Zurich, Zurich, Switzerland; and.
  • Thöny B; Department of Pediatrics, Division of Metabolism, University of Zurich, Zurich, Switzerland; and.
  • De Bleser P; Inflammation Research Center, Vlaams Instituut voor Biotechnologie, and Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • VandenDriessche T; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium; Center for Molecular and Vascular Biology, Department of Cardiovascular Medicine, University of Leuven, Leuven, Belgium;
  • Chuah MK; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, Brussels, Belgium; Center for Molecular and Vascular Biology, Department of Cardiovascular Medicine, University of Leuven, Leuven, Belgium;
Blood ; 123(20): 3195-9, 2014 May 15.
Article en En | MEDLINE | ID: mdl-24637359
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor IX / Hemofilia B / Elementos Reguladores de la Transcripción / Vectores Genéticos / Hígado Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor IX / Hemofilia B / Elementos Reguladores de la Transcripción / Vectores Genéticos / Hígado Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article