Genetic or pharmacologic disruption of the calcineurin-nuclear factor of activated T-cells axis prevents social stress-induced voiding dysfunction in a murine model.

Long, C J; Butler, S; Fesi, J; Frank, C; Canning, D A; Zderic, S A

Long, C J; Butler, S; Fesi, J; Frank, C; Canning, D A; Zderic, S A.

Afiliación

Long CJ; John W. Duckett Center for Pediatric Urology at The Children's Hospital of Philadelphia, USA; The Perelman School of Medicine at The University of Pennsylvania, USA. Electronic address: loncg3@email.chop.edu.
Butler S; John W. Duckett Center for Pediatric Urology at The Children's Hospital of Philadelphia, USA; The Perelman School of Medicine at The University of Pennsylvania, USA. Electronic address: butlers@email.chop.edu.
Fesi J; John W. Duckett Center for Pediatric Urology at The Children's Hospital of Philadelphia, USA; The Perelman School of Medicine at The University of Pennsylvania, USA. Electronic address: sliwoski@email.chop.edu.
Frank C; John W. Duckett Center for Pediatric Urology at The Children's Hospital of Philadelphia, USA; The Perelman School of Medicine at The University of Pennsylvania, USA. Electronic address: charles.frank@emory.edu.
Canning DA; John W. Duckett Center for Pediatric Urology at The Children's Hospital of Philadelphia, USA; The Perelman School of Medicine at The University of Pennsylvania, USA. Electronic address: canning@email.chop.edu.
Zderic SA; John W. Duckett Center for Pediatric Urology at The Children's Hospital of Philadelphia, USA. Electronic address: zderic@email.chop.edu.

J Pediatr Urol ; 10(4): 598-604, 2014 Aug.

Article en En | MEDLINE | ID: mdl-24909609

Asunto(s)

Inhibidores de la Calcineurina/uso terapéutico; Factores de Transcripción NFATC/genética; Estrés Psicológico/complicaciones; Trastornos Urinarios/etiología; Trastornos Urinarios/prevención & control; Animales; Hormona Liberadora de Corticotropina/genética; Hormona Liberadora de Corticotropina/metabolismo; Ciclosporina/uso terapéutico; Modelos Animales de Enfermedad; Femenino; Masculino; Ratones; Ratones Noqueados; ARN Mensajero/metabolismo

Palabras clave

Barrington's nucleus; Corticotropin releasing factor; Nuclear factor of activated T-cells; Social stress; Voiding dysfunction

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Estrés Psicológico / Trastornos Urinarios / Factores de Transcripción NFATC / Inhibidores de la Calcineurina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Pediatr Urol Año: 2014 Tipo del documento: Article

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