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miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation.
Denoyelle, C; Lambert, B; Meryet-Figuière, M; Vigneron, N; Brotin, E; Lecerf, C; Abeilard, E; Giffard, F; Louis, M-H; Gauduchon, P; Juin, P; Poulain, L.
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  • Denoyelle C; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Lambert B; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France [4] CNRS, Délégation régionale Ile-de-France Est, 94532 Thiais cedex, France.
  • Meryet-Figuière M; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Vigneron N; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Brotin E; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Lecerf C; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Abeilard E; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Giffard F; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Louis MH; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Gauduchon P; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
  • Juin P; 1] Team 8 Cell survival and tumor escape in breast cancer, UMR 892 INSERM/6299 CNRS, Université de Nantes, Institut de Recherche Thérapeutique de l'Université de Nantes, Nantes, France [2] Institut de Cancérologie de l'Ouest (ICO), Centre de Lutte contre le Cancer René Gauducheau, Angers, France.
  • Poulain L; 1] Normandie Univ, Caen, France [2] UNICAEN BioTICLA Unit (Biology and innovative therapeutics of locally aggressive cancers) EA4656, Caen, France [3] Comprehensive Cancer Center François Baclesse, UNICANCER, Caen, France.
Cell Death Dis ; 5: e1445, 2014 Oct 09.
Article en En | MEDLINE | ID: mdl-25299770
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Carcinoma / Proteínas Proto-Oncogénicas / Apoptosis / MicroARNs / Proteínas Reguladoras de la Apoptosis / Proteína bcl-X / Receptores ErbB / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Cell Death Dis Año: 2014 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Carcinoma / Proteínas Proto-Oncogénicas / Apoptosis / MicroARNs / Proteínas Reguladoras de la Apoptosis / Proteína bcl-X / Receptores ErbB / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Cell Death Dis Año: 2014 Tipo del documento: Article País de afiliación: Francia