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Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
Mankan, Arun K; Schmidt, Tobias; Chauhan, Dhruv; Goldeck, Marion; Höning, Klara; Gaidt, Moritz; Kubarenko, Andrew V; Andreeva, Liudmila; Hopfner, Karl-Peter; Hornung, Veit.
Afiliación
  • Mankan AK; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany.
  • Schmidt T; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany.
  • Chauhan D; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany.
  • Goldeck M; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital University of Bonn, Bonn, Germany.
  • Höning K; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany.
  • Gaidt M; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany.
  • Kubarenko AV; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany.
  • Andreeva L; Department of Biochemistry and Gene Center, Ludwig-Maximilians-University, Munich, Germany.
  • Hopfner KP; Department of Biochemistry and Gene Center, Ludwig-Maximilians-University, Munich, Germany.
  • Hornung V; Institute of Molecular Medicine, University Hospital University of Bonn, Bonn, Germany veit.hornung@uni-bonn.de.
EMBO J ; 33(24): 2937-46, 2014 Dec 17.
Article en En | MEDLINE | ID: mdl-25425575
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus / ADN / ARN / Proteínas de la Membrana / Hibridación de Ácido Nucleico / Nucleótidos Cíclicos / Nucleotidiltransferasas Límite: Humans Idioma: En Revista: EMBO J Año: 2014 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus / ADN / ARN / Proteínas de la Membrana / Hibridación de Ácido Nucleico / Nucleótidos Cíclicos / Nucleotidiltransferasas Límite: Humans Idioma: En Revista: EMBO J Año: 2014 Tipo del documento: Article País de afiliación: Alemania