Inhibiting EGFR clustering and cell proliferation with gold nanoparticles.
Small
; 11(14): 1638-43, 2015 Apr 08.
Article
en En
| MEDLINE
| ID: mdl-25504553
ABSTRACT
Gold nanoparticles are functionalized with epidermal growth factor (EGF) molecules and incubated with HeLa cells. These new complexes mechanically interfere with the activation of EGF receptors in a length-dependent manner. Protein-functionalized gold nanoparticles hold great potential for unveiling the fundamental characteristics of cell receptors and for future pharmacological studies on receptor targeting.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proliferación Celular
/
Nanopartículas del Metal
/
Receptores ErbB
/
Oro
Límite:
Humans
Idioma:
En
Revista:
Small
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Australia