Chemical constituents from the aerial parts of Melandrium firmum.
Arch Pharm Res
; 38(10): 1746-51, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-25575626
ABSTRACT
Two new anthraquinones, melrubiellin C (1) and melrubiellin D (2), were isolated from the aerial parts of Melandrium firmum Rohrbach, together with eight known compounds (3-10). The structures of these compounds were elucidated using 1D and 2D NMR (COSY, HMQC, HMBC and NOESY) experiments. All isolated compounds were tested for their cytotoxicity against NCI-H460, Hep G2, MKN-28 and A-549 cells. Of these 10 compounds, 1 and 2 exhibited moderate cytotoxicity with IC50 values ranging from 9.54 to 32.41 µM.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Caryophyllaceae
/
Neoplasias
/
Antineoplásicos Fitogénicos
Límite:
Humans
Idioma:
En
Revista:
Arch Pharm Res
Año:
2015
Tipo del documento:
Article
País de afiliación:
China