Suppression of adrenal ßarrestin1-dependent aldosterone production by ARBs: head-to-head comparison.

Dabul, Samalia; Bathgate-Siryk, Ashley; Valero, Thairy Reyes; Jafferjee, Malika; Sturchler, Emmanuel; McDonald, Patricia; Koch, Walter J; Lymperopoulos, Anastasios

Dabul, Samalia; Bathgate-Siryk, Ashley; Valero, Thairy Reyes; Jafferjee, Malika; Sturchler, Emmanuel; McDonald, Patricia; Koch, Walter J; Lymperopoulos, Anastasios.

Afiliación

Dabul S; Laboratory for the Study of Neurohormonal Control of the Circulation, Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL 33328, USA.
Bathgate-Siryk A; Laboratory for the Study of Neurohormonal Control of the Circulation, Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL 33328, USA.
Valero TR; Laboratory for the Study of Neurohormonal Control of the Circulation, Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL 33328, USA.
Jafferjee M; Laboratory for the Study of Neurohormonal Control of the Circulation, Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL 33328, USA.
Sturchler E; Translational Research Institute, Scripps Florida, Jupiter, FL 33458, USA.
McDonald P; Translational Research Institute, Scripps Florida, Jupiter, FL 33458, USA.
Koch WJ; Center for Translational Medicine, Temple University, Philadelphia, PA 19140, USA.
Lymperopoulos A; Laboratory for the Study of Neurohormonal Control of the Circulation, Department of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL 33328, USA.

Sci Rep ; 5: 8116, 2015 Jan 29.

Article en En | MEDLINE | ID: mdl-25631300

Asunto(s)

Glándulas Suprarrenales/metabolismo; Aldosterona/biosíntesis; Antagonistas de Receptores de Angiotensina/farmacología; Arrestinas/metabolismo; Angiotensina II/farmacología; Antagonistas de Receptores de Angiotensina/química; Animales; Bencimidazoles/farmacología; Compuestos de Bifenilo; Células CHO; Cricetinae; Cricetulus; Proteínas de Unión al GTP/metabolismo; Humanos; Fosfoproteínas/metabolismo; Ratas; Receptor de Angiotensina Tipo 1/metabolismo; Tetrazoles/farmacología; Regulación hacia Arriba/efectos de los fármacos; Valina/análogos & derivados; Valina/farmacología; Valsartán; Zona Glomerular; beta-Arrestinas

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Glándulas Suprarrenales / Arrestinas / Aldosterona / Antagonistas de Receptores de Angiotensina Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

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