Teaching old drugs new tricks to stop malaria invasion in its tracks.
BMC Biol
; 13: 72, 2015 Sep 08.
Article
en En
| MEDLINE
| ID: mdl-26349580
ABSTRACT
Malaria is a common and life-threatening disease endemic in large parts of the world. The emergence of antimalarial drug resistance is threatening disease-control measures that depend heavily on treatment of clinical malaria. The intracellular malaria parasite is particularly vulnerable during its brief extracellular stage of the life cycle. Wilson et al. describe a screen targeting these extracellular parasite stages and make the surprising discovery that clinically used macrolide antibiotics are potent inhibitors of parasite invasion into erythrocytes.See research article http//www.biomedcentral.com/1741-7007/13/52.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Plasmodium berghei
/
Plasmodium falciparum
/
Eritromicina
/
Azitromicina
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Eritrocitos
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Malaria
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Antimaláricos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
BMC Biol
Asunto de la revista:
BIOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos