Regulation of neuronal migration, an emerging topic in autism spectrum disorders.
J Neurochem
; 136(3): 440-56, 2016 Feb.
Article
en En
| MEDLINE
| ID: mdl-26485324
ABSTRACT
Autism spectrum disorders (ASD) encompass a group of neurodevelopmental diseases that demonstrate strong heritability, however, the inheritance is not simple and many genes have been associated with these disorders. ASD is regarded as a neurodevelopmental disorder, and abnormalities at different developmental stages are part of the disease etiology. This review provides a general background on neuronal migration during brain development and discusses recent advancements in the field connecting ASD and aberrant neuronal migration. We propose that neuronal migration impairment may be an important common pathophysiology in autism spectrum disorders (ASD). This review provides a general background on neuronal migration during brain development and discusses recent advancements in the field connecting ASD and aberrant neuronal migration.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Movimiento Celular
/
Trastorno del Espectro Autista
/
Neuronas
Límite:
Humans
Idioma:
En
Revista:
J Neurochem
Año:
2016
Tipo del documento:
Article
País de afiliación:
Israel