Your browser doesn't support javascript.
loading
Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled.
Lee, Ho-Jin; Bao, Ju; Miller, Ami; Zhang, Chi; Wu, Jibo; Baday, Yiressy C; Guibao, Cristina; Li, Lin; Wu, Dianqing; Zheng, Jie J.
Afiliación
  • Lee HJ; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
  • Bao J; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
  • Miller A; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
  • Zhang C; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, the Department of Ophthalmology, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095.
  • Wu J; the State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, and the Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510.
  • Baday YC; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
  • Guibao C; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
  • Li L; the State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, and.
  • Wu D; the Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510.
  • Zheng JJ; From the Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, the Department of Ophthalmology, Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, jzheng@jsei.ucla.edu.
J Biol Chem ; 290(51): 30596-606, 2015 Dec 18.
Article en En | MEDLINE | ID: mdl-26504084

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Frizzled / Vía de Señalización Wnt / Simulación del Acoplamiento Molecular / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Frizzled / Vía de Señalización Wnt / Simulación del Acoplamiento Molecular / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article