Azole Resistance in Aspergillus fumigatus Clinical Isolates from an Italian Culture Collection.
Antimicrob Agents Chemother
; 60(1): 682-5, 2016 01.
Article
en En
| MEDLINE
| ID: mdl-26552980
The aims of the study were to investigate the prevalence of azole resistance among Aspergillus fumigatus clinical isolates. A total of 533 clinical isolates that had been collected between 1995 and 2006, from 441 patients, were screened. No resistance was detected in isolates collected between 1995 and 1997. Starting in 1998, the resistance rate was 6.9%; a total of 24 patients (6.25%) harbored a resistant isolate. The TR34/L98H substitution was found in 21 of 30 tested isolates.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Aspergilosis
/
Aspergillus fumigatus
/
Proteínas Fúngicas
/
Sistema Enzimático del Citocromo P-450
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Farmacorresistencia Fúngica
/
Antifúngicos
Tipo de estudio:
Risk_factors_studies
/
Screening_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2016
Tipo del documento:
Article
País de afiliación:
Italia