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Potent irreversible P2Y12 inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial.
Schoergenhofer, Christian; Schwameis, Michael; Hobl, Eva-Luise; Ay, Cihan; Key, Nigel S; Derhaschnig, Ulla; Jilma, Bernd; Spiel, Alexander O.
Afiliación
  • Schoergenhofer C; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
  • Schwameis M; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
  • Hobl EL; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
  • Ay C; Department of Internal Medicine I, Clinical Division of Hematology and Hemostaseology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
  • Key NS; Hemophilia and Thrombosis Center, Department of Medicine, UNC Chapel Hill, 170 Manning Drive, Chapel Hill, NC 27514, U.S.A.
  • Derhaschnig U; Department of Emergency Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
  • Jilma B; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria Bernd.jilma@meduniwien.ac.at.
  • Spiel AO; Department of Emergency Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Clin Sci (Lond) ; 130(6): 433-40, 2016 Mar.
Article en En | MEDLINE | ID: mdl-26554025
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Coagulación Sanguínea / Inhibidores de Agregación Plaquetaria / Activación Plaquetaria / Antagonistas del Receptor Purinérgico P2Y / Clorhidrato de Prasugrel Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Clin Sci (Lond) Año: 2016 Tipo del documento: Article País de afiliación: Austria
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Coagulación Sanguínea / Inhibidores de Agregación Plaquetaria / Activación Plaquetaria / Antagonistas del Receptor Purinérgico P2Y / Clorhidrato de Prasugrel Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Clin Sci (Lond) Año: 2016 Tipo del documento: Article País de afiliación: Austria