A natural reassortant and mutant serotype 3 reovirus from mink in China.
Arch Virol
; 161(2): 495-8, 2016 Feb.
Article
en En
| MEDLINE
| ID: mdl-26573525
ABSTRACT
Mammalian orthoreoviruses (MRVs) are widespread and infect virtually all mammals. We report here the first case of a natural mutant and reassortant serotype 3 reovirus from mink in China, known as MRV3 SD-14. Whole-genome sequence analysis showed that the MRV3 SD-14 may have resulted from a reassortment involving MRVs that infected swine, humans and mink. Interestingly, the S1 segment, which encodes the viral attachment protein σ1, which influences viral virulence and cell tropism in the host, had a stop codon mutation at amino acid 246. Surveillance of the virulence and evolution of MRVs in humans and other animals deserves more attention.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Orthoreovirus Mamífero 3
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ARN Viral
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Virus Reordenados
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Genoma Viral
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Visón
Límite:
Animals
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Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Arch Virol
Año:
2016
Tipo del documento:
Article
País de afiliación:
China