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Responses to the multitargeted MET/ALK/ROS1 inhibitor crizotinib and co-occurring mutations in lung adenocarcinomas with MET amplification or MET exon 14 skipping mutation.
Jorge, Susan E; Schulman, Sol; Freed, Jason A; VanderLaan, Paul A; Rangachari, Deepa; Kobayashi, Susumu S; Huberman, Mark S; Costa, Daniel B.
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  • Jorge SE; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • Schulman S; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • Freed JA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • VanderLaan PA; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • Rangachari D; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • Kobayashi SS; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • Huberman MS; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
  • Costa DB; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States. Electronic address: dbcosta@bidmc.harvard.edu.
Lung Cancer ; 90(3): 369-74, 2015 Dec.
Article en En | MEDLINE | ID: mdl-26791794
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Adenocarcinoma / Amplificación de Genes / Empalme Alternativo / Proteínas Proto-Oncogénicas c-met / Inhibidores de Proteínas Quinasas / Neoplasias Pulmonares / Mutación / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Adenocarcinoma / Amplificación de Genes / Empalme Alternativo / Proteínas Proto-Oncogénicas c-met / Inhibidores de Proteínas Quinasas / Neoplasias Pulmonares / Mutación / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos