HilbertCurve: an R/Bioconductor package for high-resolution visualization of genomic data.

ABSTRACT

UNLABELLED Hilbert curves enable high-resolution visualization of genomic data on a chromosome- or genome-wide scale. Here we present the HilbertCurve package that provides an easy-to-use interface for mapping genomic data to Hilbert curves. The package transforms the curve as a virtual axis, thereby hiding the details of the curve construction from the user. HilbertCurve supports multiple-layer overlay that makes it a powerful tool to correlate the spatial distribution of multiple feature types. AVAILABILITY AND IMPLEMENTATION The HilbertCurve package and documentation are freely available from the Bioconductor project http//www.bioconductor.org/packages/devel/bioc/html/HilbertCurve.html CONTACT m.schlesner@dkfz.de SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.