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Design, synthesis, and anticancer activity of C8-substituted-4'-thionucleosides as potential HSP90 inhibitors.
Qu, Shuhao; Mulamoottil, Varughese A; Nayak, Akshata; Ryu, Seungyeon; Hou, Xiyan; Song, Jayoung; Yu, Jinha; Sahu, Pramod K; Zhao, Long Xuan; Choi, Sun; Lee, Sang Kook; Jeong, Lak Shin.
Afiliación
  • Qu S; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea; College of Pharmacy, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Mulamoottil VA; College of Pharmacy, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Nayak A; College of Pharmacy, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Ryu S; College of Pharmacy, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Hou X; College of Life Science, Dalian Nationalities University, Dalian 116600, China.
  • Song J; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Yu J; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Sahu PK; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Zhao LX; College of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116-029, China.
  • Choi S; College of Pharmacy, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Lee SK; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
  • Jeong LS; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea. Electronic address: lakjeong@snu.ac.kr.
Bioorg Med Chem ; 24(16): 3418-28, 2016 08 15.
Article en En | MEDLINE | ID: mdl-27283788
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tionucleósidos / Proteínas HSP90 de Choque Térmico Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tionucleósidos / Proteínas HSP90 de Choque Térmico Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article