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Chromatography-based methods for determining molar extinction coefficients of cytotoxic payload drugs and drug antibody ratios of antibody drug conjugates.
Wang, Chunlei; Chen, Sike; Caceres-Cortes, Janet; Huang, Richard Y-C; Tymiak, Adrienne A; Zhang, Yingru.
Afiliación
  • Wang C; Research & Development, Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, United States. Electronic address: chunlei.wang@bms.com.
  • Chen S; Research & Development, Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, United States.
  • Caceres-Cortes J; Research & Development, Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, United States.
  • Huang RY; Research & Development, Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, United States.
  • Tymiak AA; Research & Development, Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, United States.
  • Zhang Y; Research & Development, Bristol-Myers Squibb Company, Route 206 and Province Line Road, Princeton, NJ 08543, United States.
J Chromatogr A ; 1455: 133-139, 2016 Jul 15.
Article en En | MEDLINE | ID: mdl-27286648
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoconjugados / Maitansina / Anticuerpos / Antineoplásicos Fitogénicos Idioma: En Revista: J Chromatogr A Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoconjugados / Maitansina / Anticuerpos / Antineoplásicos Fitogénicos Idioma: En Revista: J Chromatogr A Año: 2016 Tipo del documento: Article