Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia.

Shi, Xudong; Guo, Lian-Wang; Seedial, Stephen; Takayama, Toshio; Wang, Bowen; Zhang, Mengxue; Franco, Sarah R; Si, Yi; Chaudhary, Mirnal A; Liu, Bo; Kent, K Craig

Shi, Xudong; Guo, Lian-Wang; Seedial, Stephen; Takayama, Toshio; Wang, Bowen; Zhang, Mengxue; Franco, Sarah R; Si, Yi; Chaudhary, Mirnal A; Liu, Bo; Kent, K Craig.

Afiliación

Shi X; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Guo LW; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Seedial S; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Takayama T; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Wang B; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Zhang M; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Franco SR; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Si Y; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Chaudhary MA; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Liu B; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Kent KC; Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

Stem Cells ; 34(11): 2744-2757, 2016 11.

Article en En | MEDLINE | ID: mdl-27340942

Asunto(s)

Traumatismos de las Arterias Carótidas/genética; Neointima/genética; Receptores CXCR4/genética; Proteína smad3/genética; Factor de Crecimiento Transformador beta/metabolismo; Túnica Íntima/metabolismo; Animales; Arterias Carótidas/metabolismo; Traumatismos de las Arterias Carótidas/metabolismo; Traumatismos de las Arterias Carótidas/patología; Movimiento Celular; Regulación de la Expresión Génica; Masculino; Ratones; Ratones Noqueados; Proteínas de Microfilamentos/genética; Proteínas de Microfilamentos/metabolismo; Proteína Quinasa 1 Activada por Mitógenos/genética; Proteína Quinasa 1 Activada por Mitógenos/metabolismo; Proteína Quinasa 3 Activada por Mitógenos/genética; Proteína Quinasa 3 Activada por Mitógenos/metabolismo; Proteínas Musculares/genética; Proteínas Musculares/metabolismo; Miocitos del Músculo Liso/citología; Miocitos del Músculo Liso/efectos de los fármacos; Miocitos del Músculo Liso/metabolismo; Neointima/metabolismo; Neointima/patología; Fosforilación; Cultivo Primario de Células; Regiones Promotoras Genéticas; Ratas; Ratas Sprague-Dawley; Receptores CXCR4/deficiencia; Transducción de Señal; Proteína smad3/metabolismo; Factor de Crecimiento Transformador beta/farmacología; Túnica Íntima/lesiones

Palabras clave

CXCR4/SDF-1α; TGFß/Smad3; intimal hyperplasia; smooth muscle cell migration; smooth muscle cell specific CXCR4 knockout

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta / Túnica Íntima / Receptores CXCR4 / Traumatismos de las Arterias Carótidas / Proteína smad3 / Neointima Idioma: En Revista: Stem Cells Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos

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