Ischemic aetiology, self-reported frailty, and gender with respect to cognitive impairment in chronic heart failure patients.
BMC Cardiovasc Disord
; 16(1): 163, 2016 08 30.
Article
en En
| MEDLINE
| ID: mdl-27577747
ABSTRACT
BACKGROUND:
Decisive information on the parameters involved in cognitive impairment in patients with chronic heart failure is as yet lacking. Our aim was to determine the functional and psychosocial variables related with cognitive impairment using the mini-mental-state examination (MMSE) with age-and education-corrected scores.METHODS:
A cohort study of chronic heart failure patients included in an integrated multidisciplinary hospital/primary care program. The MMSE (corrected for age and education in the Spanish population) was administered at enrolment in the program. Analyses were performed in 525 patients. Demographic and clinical variables were collected. Comprehensive assessment included depression (Yesavage), family function (family APGAR), social network (Duke), dependence (Barthel Index), frailty (Barber), and comorbidities. Univariate and multivariate logistic regression were performed to determine the predictors of cognitive impairment.RESULTS:
Cognitive impairment affected 145 patients (27.6 %). Explanatory factors were gender (OR 2.77 (1.75-4.39) p < 0.001), ischemic etiology (OR 1.99 (1.25-3.17) p = 0.004), frailty (OR 1.58 (0.99 to 2.50, p =0.050), albumin > 3.5 (OR 0.59 (0.35-0.99) p = 0.048), and beta-blocker treatment (OR 0.36 (0.17 to 0.76, p = 0.007)). No association was found between cognitive impairment and social support or family function.CONCLUSION:
The observed prevalence of cognitive impairment using MMSE corrected scores was 27.6 %. A global approach in the management of these patients is needed, especially focusing on women and patients with frailty, low albumin levels, and ischemic aetiology heart failure.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Anciano Frágil
/
Isquemia Miocárdica
/
Autoinforme
/
Disfunción Cognitiva
/
Insuficiencia Cardíaca
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
BMC Cardiovasc Disord
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
España