Stop codons in the hepatitis B surface proteins are enriched during antiviral therapy and are associated with host cell apoptosis.

Colledge, Danielle; Soppe, Sally; Yuen, Lilly; Selleck, Lucy; Walsh, Renae; Locarnini, Stephen; Warner, Nadia

Colledge, Danielle; Soppe, Sally; Yuen, Lilly; Selleck, Lucy; Walsh, Renae; Locarnini, Stephen; Warner, Nadia.

Afiliación

Colledge D; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia.
Soppe S; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia.
Yuen L; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia.
Selleck L; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia.
Walsh R; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia.
Locarnini S; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia. Electronic address: stephen.locarnini@mh.org.au.
Warner N; Molecular Research and Development, Victorian Infectious Diseases Reference Laboratories, Melbourne, Victoria, Australia.

Virology ; 501: 70-78, 2017 01 15.

Article en En | MEDLINE | ID: mdl-27871021

Asunto(s)

Antivirales/administración & dosificación; Apoptosis; Codón de Terminación/genética; Antígenos de Superficie de la Hepatitis B/genética; Virus de la Hepatitis B/efectos de los fármacos; Virus de la Hepatitis B/genética; Hepatitis B/fisiopatología; Hepatitis B/tratamiento farmacológico; Hepatitis B/virología; Antígenos de Superficie de la Hepatitis B/metabolismo; Virus de la Hepatitis B/fisiología; Humanos; Replicación Viral

Palabras clave

Apoptosis; Cytopathic variant; Hepatitis B virus; Nucleos(t)ide analogue resistance; Pathogenic variants; Surface stop codons

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antivirales / Virus de la Hepatitis B / Apoptosis / Codón de Terminación / Hepatitis B / Antígenos de Superficie de la Hepatitis B Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Virology Año: 2017 Tipo del documento: Article País de afiliación: Australia

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