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Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Zheng, Yi; Qin, Ling; Zacarías, Natalia V Ortiz; de Vries, Henk; Han, Gye Won; Gustavsson, Martin; Dabros, Marta; Zhao, Chunxia; Cherney, Robert J; Carter, Percy; Stamos, Dean; Abagyan, Ruben; Cherezov, Vadim; Stevens, Raymond C; IJzerman, Adriaan P; Heitman, Laura H; Tebben, Andrew; Kufareva, Irina; Handel, Tracy M.
Afiliación
  • Zheng Y; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
  • Qin L; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
  • Zacarías NV; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden 2333 CC, The Netherlands.
  • de Vries H; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden 2333 CC, The Netherlands.
  • Han GW; Bridge Institute, Departments of Chemistry and Physics &Astronomy, University of Southern California, Los Angeles, California 90089, USA.
  • Gustavsson M; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
  • Dabros M; Bristol-Myers Squibb Company, Princeton, New Jersey 08543, USA.
  • Zhao C; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
  • Cherney RJ; Bristol-Myers Squibb Company, Princeton, New Jersey 08543, USA.
  • Carter P; Bristol-Myers Squibb Company, Princeton, New Jersey 08543, USA.
  • Stamos D; Vertex Pharmaceuticals Inc., 11010 Torreyana Road, San Diego, California 92121, USA.
  • Abagyan R; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
  • Cherezov V; Bridge Institute, Departments of Chemistry and Physics &Astronomy, University of Southern California, Los Angeles, California 90089, USA.
  • Stevens RC; The Bridge Institute, Departments of Biological Sciences and Chemistry, University of Southern California, Los Angeles, California 90089, USA.
  • IJzerman AP; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden 2333 CC, The Netherlands.
  • Heitman LH; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (LACDR), Leiden University, Leiden 2333 CC, The Netherlands.
  • Tebben A; Bristol-Myers Squibb Company, Princeton, New Jersey 08543, USA.
  • Kufareva I; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
  • Handel TM; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
Nature ; 540(7633): 458-461, 2016 12 15.
Article en En | MEDLINE | ID: mdl-27926736
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirrolidinonas / Quinazolinas / Receptores CCR2 Límite: Humans Idioma: En Revista: Nature Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirrolidinonas / Quinazolinas / Receptores CCR2 Límite: Humans Idioma: En Revista: Nature Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos