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Presenilin 2 deficiency facilitates Aß-induced neuroinflammation and injury by upregulating P2X7 expression.
Qin, Juliang; Zhang, Xiaoyu; Wang, Ziqiang; Li, Jinju; Zhang, Zhen; Gao, Liangcai; Ren, Hua; Qian, Min; Du, Bing.
Afiliación
  • Qin J; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Zhang X; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Wang Z; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Li J; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Zhang Z; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Gao L; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Ren H; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
  • Qian M; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. mqian@bio.ecnu.edu.cn.
  • Du B; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. bdu.ecnu@gmail.com.
Sci China Life Sci ; 60(2): 189-201, 2017 Feb.
Article en En | MEDLINE | ID: mdl-28120269
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Péptidos beta-Amiloides / Presenilina-2 / Receptores Purinérgicos P2X7 / Enfermedad de Alzheimer / Neuronas Límite: Animals Idioma: En Revista: Sci China Life Sci Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Péptidos beta-Amiloides / Presenilina-2 / Receptores Purinérgicos P2X7 / Enfermedad de Alzheimer / Neuronas Límite: Animals Idioma: En Revista: Sci China Life Sci Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: China