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Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells.
Lai, Jiun-I; Leman, Luke J; Ku, Sherman; Vickers, Chris J; Olsen, Christian A; Montero, Ana; Ghadiri, M Reza; Gottesfeld, Joel M.
Afiliación
  • Lai JI; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA; National Yang-Ming University, Taipei, Taiwan; National Yang-Ming University Hospital, Ilan, Taiwan.
  • Leman LJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
  • Ku S; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA.
  • Vickers CJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
  • Olsen CA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA; Center for Biopharmaceuticals and Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
  • Montero A; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
  • Ghadiri MR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
  • Gottesfeld JM; Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA. Electronic address: joelg@scripps.edu.
Bioorg Med Chem Lett ; 27(15): 3289-3293, 2017 08 01.
Article en En | MEDLINE | ID: mdl-28648462
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Atrofia Muscular Espinal / Inhibidores de Histona Desacetilasas / Neuronas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Taiwán
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Atrofia Muscular Espinal / Inhibidores de Histona Desacetilasas / Neuronas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Taiwán