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Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.
Wang, Zhi-Hao; Liu, Pai; Liu, Xia; Manfredsson, Fredric P; Sandoval, Ivette M; Yu, Shan Ping; Wang, Jian-Zhi; Ye, Keqiang.
Afiliación
  • Wang ZH; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA; Department of Pathophysiology, Key Laboratory of Ministry of Education of Neurological Diseases, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Liu P; Emory College of Arts and Sciences, Emory University, Atlanta, GA 30322, USA.
  • Liu X; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Manfredsson FP; Department of Translational Science and Molecular Medicine, Michigan State University, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA.
  • Sandoval IM; Department of Translational Science and Molecular Medicine, Michigan State University, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA.
  • Yu SP; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Wang JZ; Department of Pathophysiology, Key Laboratory of Ministry of Education of Neurological Diseases, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Co-innovation Center of Neuroregeneration, Nantong 226001, China. Electronic address: wangjz@mails.tjmu.edu.cn.
  • Ye K; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA; Translational Center for Stem Cell Research, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China. Electronic address: kye@emory.edu.
Mol Cell ; 67(5): 812-825.e5, 2017 Sep 07.
Article en En | MEDLINE | ID: mdl-28826672
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Procesamiento Proteico-Postraduccional / Proteínas Serina-Treonina Quinasas / Secretasas de la Proteína Precursora del Amiloide / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Procesamiento Proteico-Postraduccional / Proteínas Serina-Treonina Quinasas / Secretasas de la Proteína Precursora del Amiloide / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: China