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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.
Mass, Elvira; Jacome-Galarza, Christian E; Blank, Thomas; Lazarov, Tomi; Durham, Benjamin H; Ozkaya, Neval; Pastore, Alessandro; Schwabenland, Marius; Chung, Young Rock; Rosenblum, Marc K; Prinz, Marco; Abdel-Wahab, Omar; Geissmann, Frederic.
Afiliación
  • Mass E; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Jacome-Galarza CE; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Blank T; Institute of Neuropathology, Faculty of Medicine, BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
  • Lazarov T; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Durham BH; Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Ozkaya N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Pastore A; Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Schwabenland M; Institute of Neuropathology, Faculty of Medicine, BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
  • Chung YR; Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Rosenblum MK; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Prinz M; Institute of Neuropathology, Faculty of Medicine, BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
  • Abdel-Wahab O; Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
  • Geissmann F; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Nature ; 549(7672): 389-393, 2017 09 21.
Article en En | MEDLINE | ID: mdl-28854169

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Precursoras Eritroides / Enfermedades Neurodegenerativas / Sistema de Señalización de MAP Quinasas / Células Progenitoras Mieloides / Proteínas Proto-Oncogénicas B-raf / Mutación Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Precursoras Eritroides / Enfermedades Neurodegenerativas / Sistema de Señalización de MAP Quinasas / Células Progenitoras Mieloides / Proteínas Proto-Oncogénicas B-raf / Mutación Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nature Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos