Potential of GHB phase-II-metabolites to complement current approaches in GHB post administration detection.

Piper, Thomas; Mehling, Lena-Maria; Spottke, Annika; Heidbreder, Anna; Young, Peter; Madea, Burkhard; Hess, Cornelius; Schänzer, Wilhelm; Thevis, Mario

Piper, Thomas; Mehling, Lena-Maria; Spottke, Annika; Heidbreder, Anna; Young, Peter; Madea, Burkhard; Hess, Cornelius; Schänzer, Wilhelm; Thevis, Mario.

Afiliación

Piper T; German Sport University Cologne, Center for Preventive Doping Research, Am Sportpark Müngersdorf 6, 50933 Köln, Germany. Electronic address: t.piper@biochem.dshs-koeln.de.
Mehling LM; Institute of Forensic Medicine, University of Bonn, Stiftsplatz 12, 53111 Bonn, Germany.
Spottke A; Department of Neurology, University Hospital, University of Bonn, Sigmund-Freud-Straße 25, 53127 Bonn, Germany.
Heidbreder A; Division of Sleep Medicine and Neuromuscular Disorders, Department of Neurology, University Hospital, University of Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.
Young P; Division of Sleep Medicine and Neuromuscular Disorders, Department of Neurology, University Hospital, University of Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.
Madea B; Institute of Forensic Medicine, University of Bonn, Stiftsplatz 12, 53111 Bonn, Germany.
Hess C; Institute of Forensic Medicine, University of Bonn, Stiftsplatz 12, 53111 Bonn, Germany.
Schänzer W; German Sport University Cologne, Center for Preventive Doping Research, Am Sportpark Müngersdorf 6, 50933 Köln, Germany.
Thevis M; German Sport University Cologne, Center for Preventive Doping Research, Am Sportpark Müngersdorf 6, 50933 Köln, Germany.

Forensic Sci Int ; 279: 157-164, 2017 Oct.

Article en En | MEDLINE | ID: mdl-28869822

Asunto(s)

Glucurónidos/orina; Hidroxibutiratos/orina; Oxibato de Sodio/orina; Detección de Abuso de Sustancias/métodos; Sulfatos/orina; Biomarcadores/orina; Estudios de Casos y Controles; Semivida; Humanos; Metabolómica

Palabras clave

Excretion study; GHB-4-sulfate; GHB-ß-O-glucuronide; Metabolomics; Î³-Hydroxybutyric acid (GHB)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxibato de Sodio / Sulfatos / Detección de Abuso de Sustancias / Glucurónidos / Hidroxibutiratos Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies Límite: Humans Idioma: En Revista: Forensic Sci Int Año: 2017 Tipo del documento: Article

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