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Inhibition of USP10 induces degradation of oncogenic FLT3.
Weisberg, Ellen L; Schauer, Nathan J; Yang, Jing; Lamberto, Ilaria; Doherty, Laura; Bhatt, Shruti; Nonami, Atsushi; Meng, Chengcheng; Letai, Anthony; Wright, Renee; Tiv, Hong; Gokhale, Prafulla C; Ritorto, Maria Stella; De Cesare, Virginia; Trost, Matthias; Christodoulou, Alexandra; Christie, Amanda; Weinstock, David M; Adamia, Sophia; Stone, Richard; Chauhan, Dharminder; Anderson, Kenneth C; Seo, Hyuk-Soo; Dhe-Paganon, Sirano; Sattler, Martin; Gray, Nathanael S; Griffin, James D; Buhrlage, Sara J.
Afiliación
  • Weisberg EL; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Schauer NJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Yang J; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Lamberto I; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Doherty L; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Bhatt S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Nonami A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Meng C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Wright R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Tiv H; Experimental Therapeutic Core, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Gokhale PC; Experimental Therapeutic Core, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Ritorto MS; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, Scotland, UK.
  • De Cesare V; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, Scotland, UK.
  • Trost M; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, Scotland, UK.
  • Christodoulou A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Christie A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Adamia S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Stone R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Chauhan D; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Anderson KC; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Seo HS; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Dhe-Paganon S; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Sattler M; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Gray NS; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Griffin JD; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.
  • Buhrlage SJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
Nat Chem Biol ; 13(12): 1207-1215, 2017 Dec.
Article en En | MEDLINE | ID: mdl-28967922
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tiofenos / Leucemia Mieloide Aguda / Ubiquitina Tiolesterasa / Inhibidores de Proteínas Quinasas / Tirosina Quinasa 3 Similar a fms / Bibliotecas de Moléculas Pequeñas / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tiofenos / Leucemia Mieloide Aguda / Ubiquitina Tiolesterasa / Inhibidores de Proteínas Quinasas / Tirosina Quinasa 3 Similar a fms / Bibliotecas de Moléculas Pequeñas / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos