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The anthraquinone emodin inhibits the non-exported FIKK kinase from Plasmodium falciparum.
Lin, Benjamin C; Harris, Darcy R; Kirkman, Lucy M D; Perez, Astrid M; Qian, Yiwen; Schermerhorn, Janse T; Hong, Min Y; Winston, Dennis S; Xu, Lingyin; Lieber, Alexander M; Hamilton, Matthew; Brandt, Gabriel S.
Afiliación
  • Lin BC; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Harris DR; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Kirkman LMD; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Perez AM; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Qian Y; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Schermerhorn JT; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Hong MY; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Winston DS; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Xu L; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Lieber AM; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Hamilton M; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States.
  • Brandt GS; Department of Chemistry, Franklin & Marshall College, Lancaster, PA, United States. Electronic address: gbrandt@fandm.edu.
Bioorg Chem ; 75: 217-223, 2017 12.
Article en En | MEDLINE | ID: mdl-28987877

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Proteínas Quinasas / Proteínas Protozoarias / Emodina Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Proteínas Quinasas / Proteínas Protozoarias / Emodina Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos