Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8<sup>+</sup> T Cell Responses to Chronic Viral Infections and Cancer.

Okoye, Isobel S; Houghton, Michael; Tyrrell, Lorne; Barakat, Khaled; Elahi, Shokrollah

Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8⁺ T Cell Responses to Chronic Viral Infections and Cancer.

Okoye, Isobel S; Houghton, Michael; Tyrrell, Lorne; Barakat, Khaled; Elahi, Shokrollah.

Afiliación

Okoye IS; Department of Dentistry, University of Alberta, Edmonton, AB, Canada.
Houghton M; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.
Tyrrell L; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.
Barakat K; Faculty of Medicine and Dentistry, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB, Canada.
Elahi S; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.

Front Immunol ; 8: 1215, 2017.

Article en En | MEDLINE | ID: mdl-29033936

Palabras clave

T cell exhaustion; cancer; checkpoint blockade; chronic infections; immune checkpoints; immunotherapy

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Front Immunol Año: 2017 Tipo del documento: Article País de afiliación: Canadá

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