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A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.
Panganiban, Ronald A; Sun, Maoyun; Dahlin, Amber; Park, Hae-Ryung; Kan, Mengyuan; Himes, Blanca E; Mitchel, Jennifer A; Iribarren, Carlos; Jorgenson, Eric; Randell, Scott H; Israel, Elliot; Tantisira, Kelan; Shore, Stephanie; Park, Jin-Ah; Weiss, Scott T; Wu, Ann Chen; Lu, Quan.
Afiliación
  • Panganiban RA; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass.
  • Sun M; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass.
  • Dahlin A; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
  • Park HR; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass.
  • Kan M; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Himes BE; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Mitchel JA; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass.
  • Iribarren C; Division of Research, Kaiser Permanente Northern California, Oakland, Calif.
  • Jorgenson E; Division of Research, Kaiser Permanente Northern California, Oakland, Calif.
  • Randell SH; Marsico Lung Institute/Cystic Fibrosis Center, University of North Carolina, Chapel Hill, NC.
  • Israel E; Asthma Research Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
  • Tantisira K; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
  • Shore S; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass.
  • Park JA; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass.
  • Weiss ST; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
  • Wu AC; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass; Precision Medicine Translational Research Center, Department of Population Medicine, Harvard Medical School, Boston, Mass.
  • Lu Q; Program in Molecular and Integrative Physiological Sciences, Departments of Environmental Health and Genetics & Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, Mass. Electronic address: qlu@hsph.harvard.edu.
J Allergy Clin Immunol ; 142(5): 1469-1478.e2, 2018 11.
Article en En | MEDLINE | ID: mdl-29330013
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Asma / Células Epiteliales / Piroptosis / Proteínas de Neoplasias Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Asma / Células Epiteliales / Piroptosis / Proteínas de Neoplasias Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: J Allergy Clin Immunol Año: 2018 Tipo del documento: Article