Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.

Amato, Anastasia; Lucas, Xavier; Bortoluzzi, Alessio; Wright, David; Ciulli, Alessio

Amato, Anastasia; Lucas, Xavier; Bortoluzzi, Alessio; Wright, David; Ciulli, Alessio.

Afiliación

Amato A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , James Black Centre, Dow Street , Dundee DD1 5EH , United Kingdom.
Lucas X; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , James Black Centre, Dow Street , Dundee DD1 5EH , United Kingdom.
Bortoluzzi A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , James Black Centre, Dow Street , Dundee DD1 5EH , United Kingdom.
Wright D; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , James Black Centre, Dow Street , Dundee DD1 5EH , United Kingdom.
Ciulli A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , James Black Centre, Dow Street , Dundee DD1 5EH , United Kingdom.

ACS Chem Biol ; 13(4): 915-921, 2018 04 20.

Article en En | MEDLINE | ID: mdl-29529862

Asunto(s)

Proteínas de Homeodominio/química; Fragmentos de Péptidos/química; Proteínas de Plantas/química; Dedos de Zinc; Sitios de Unión; Proteínas Cromosómicas no Histona/química; Cristalografía por Rayos X; Histonas/metabolismo; Humanos; Ligandos

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Proteínas de Plantas / Dedos de Zinc / Proteínas de Homeodominio Límite: Humans Idioma: En Revista: ACS Chem Biol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido

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