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Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles.
Yanez Arteta, Marianna; Kjellman, Tomas; Bartesaghi, Stefano; Wallin, Simonetta; Wu, Xiaoqiu; Kvist, Alexander J; Dabkowska, Aleksandra; Székely, Noémi; Radulescu, Aurel; Bergenholtz, Johan; Lindfors, Lennart.
Afiliación
  • Yanez Arteta M; Pharmaceutical Sciences iMed Biotech Unit, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden; mariann.yanezarteta@astrazeneca.com lennart.lindfors@astrazeneca.com.
  • Kjellman T; Pharmaceutical Sciences iMed Biotech Unit, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden.
  • Bartesaghi S; Cardiovascular and Metabolic Diseases iMed Bioscience, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden.
  • Wallin S; Cardiovascular and Metabolic Diseases iMed Bioscience, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden.
  • Wu X; Pharmaceutical Sciences iMed Biotech Unit, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden.
  • Kvist AJ; Discovery Science iMed Bioscience, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden.
  • Dabkowska A; Pharmaceutical Sciences iMed Biotech Unit, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden.
  • Székely N; Outstation at Maier-Leibnitz Zentrum, Jülich Centre for Neutrons Science, 857 47 Garching, Germany.
  • Radulescu A; Outstation at Maier-Leibnitz Zentrum, Jülich Centre for Neutrons Science, 857 47 Garching, Germany.
  • Bergenholtz J; Department of Chemistry and Molecular Biology, University of Gothenburg, 412 96 Gothenburg, Sweden.
  • Lindfors L; Pharmaceutical Sciences iMed Biotech Unit, AstraZeneca R&D Gothenburg, 431 83 Mölndal, Sweden; mariann.yanezarteta@astrazeneca.com lennart.lindfors@astrazeneca.com.
Proc Natl Acad Sci U S A ; 115(15): E3351-E3360, 2018 04 10.
Article en En | MEDLINE | ID: mdl-29588418
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Eritropoyetina / Sistemas de Liberación de Medicamentos / Hepatocitos / Nanopartículas / Lípidos Tipo de estudio: Evaluation_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Eritropoyetina / Sistemas de Liberación de Medicamentos / Hepatocitos / Nanopartículas / Lípidos Tipo de estudio: Evaluation_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article