NAD<sup>+</sup>-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism.

Porter, Lane C; Franczyk, Michael P; Pietka, Terri; Yamaguchi, Shintaro; Lin, Jonathan B; Sasaki, Yo; Verdin, Eric; Apte, Rajendra S; Yoshino, Jun

NAD⁺-dependent deacetylase SIRT3 in adipocytes is dispensable for maintaining normal adipose tissue mitochondrial function and whole body metabolism.

Porter, Lane C; Franczyk, Michael P; Pietka, Terri; Yamaguchi, Shintaro; Lin, Jonathan B; Sasaki, Yo; Verdin, Eric; Apte, Rajendra S; Yoshino, Jun.

Afiliación

Porter LC; Center for Human Nutrition, Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine , St. Louis, Missouri.
Franczyk MP; Center for Human Nutrition, Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine , St. Louis, Missouri.
Pietka T; Center for Human Nutrition, Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine , St. Louis, Missouri.
Yamaguchi S; Center for Human Nutrition, Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine , St. Louis, Missouri.
Lin JB; Department of Ophthalmology, Washington University School of Medicine , St. Louis, Missouri.
Sasaki Y; Department of Genetics, Washington University School of Medicine , St. Louis, Missouri.
Verdin E; Gladstone Institutes, University of California San Francisco , San Francisco, California.
Apte RS; Buck Institute for Research on Aging , Novato, California.
Yoshino J; Center for Human Nutrition, Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine , St. Louis, Missouri.

Am J Physiol Endocrinol Metab ; 315(4): E520-E530, 2018 10 01.

Article en En | MEDLINE | ID: mdl-29634313

Asunto(s)

Adipocitos/metabolismo; Tejido Adiposo/metabolismo; Metabolismo Energético/genética; Mitocondrias/metabolismo; Sirtuina 3/genética; Animales; Dieta Alta en Grasa; Ratones; Ratones Noqueados; Ratones Obesos; Sirtuina 3/metabolismo

Palabras clave

NAD+; SIRT3; adipocyte; adipose tissue; glucose metabolism; mitochondria; obesity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tejido Adiposo / Adipocitos / Metabolismo Energético / Sirtuina 3 / Mitocondrias Límite: Animals Idioma: En Revista: Am J Physiol Endocrinol Metab Asunto de la revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Año: 2018 Tipo del documento: Article

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