Antimicrobial and cytotoxic juglones from the immature exocarps of Juglans mandshurica.
Nat Prod Res
; 33(22): 3203-3209, 2019 Nov.
Article
en En
| MEDLINE
| ID: mdl-29726709
ABSTRACT
Juglonols A-C (1-3), three new juglone derivatives possessing a hydroxyethyl side chain, were isolated from an organic extract of the immature exocarps of Juglans mandshurica together with five known tetralones (4-8). Their structures were elucidated by extensive spectroscopic analyses and comparison with literature data. The new juglone derivatives exhibited inhibitory activities towards a panel of bacteria and fungi, as well as cancer cell lines. In contrast, the known tetralone homologues (4-8) appeared to be much less efficacy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Naftoquinonas
/
Juglans
/
Antiinfecciosos
Límite:
Humans
Idioma:
En
Revista:
Nat Prod Res
Año:
2019
Tipo del documento:
Article
País de afiliación:
China