VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival.

Kuklinski, Lawrence F; Yan, Shaofeng; Li, Zhongze; Fisher, Jan L; Cheng, Chao; Noelle, Randolph J; Angeles, Christina V; Turk, Mary Jo; Ernstoff, Marc S

Kuklinski, Lawrence F; Yan, Shaofeng; Li, Zhongze; Fisher, Jan L; Cheng, Chao; Noelle, Randolph J; Angeles, Christina V; Turk, Mary Jo; Ernstoff, Marc S.

Afiliación

Kuklinski LF; Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Yan S; Department of Medicine, Santa Barbara Cottage Hospital, Santa Barbara, CA, USA.
Li Z; Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Fisher JL; Biostatistics Shared Resource, Norris Cotton Cancer Center, Dartmouth-Hitchock Medical Center, Lebanon, NH, USA.
Cheng C; Department of Medicine, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Noelle RJ; Departments of Biomedical Data Sciences, Molecular and Systems Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, USA.
Angeles CV; Department of Microbiology and Immunology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Turk MJ; Department of Surgery, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Ernstoff MS; Department of Microbiology and Immunology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

Cancer Immunol Immunother ; 67(7): 1113-1121, 2018 Jul.

Article en En | MEDLINE | ID: mdl-29737375

Asunto(s)

Antígenos B7/metabolismo; Antígeno B7-H1/metabolismo; Biomarcadores de Tumor/metabolismo; Linfocitos Infiltrantes de Tumor/inmunología; Melanoma/mortalidad; Receptor de Muerte Celular Programada 1/metabolismo; Neoplasias Cutáneas/mortalidad; Antígenos B7/inmunología; Antígeno B7-H1/inmunología; Femenino; Estudios de Seguimiento; Humanos; Linfocitos Infiltrantes de Tumor/metabolismo; Masculino; Melanoma/inmunología; Melanoma/metabolismo; Melanoma/patología; Persona de Mediana Edad; Pronóstico; Receptor de Muerte Celular Programada 1/inmunología; Neoplasias Cutáneas/inmunología; Neoplasias Cutáneas/metabolismo; Neoplasias Cutáneas/patología; Tasa de Supervivencia; Microambiente Tumoral; Melanoma Cutáneo Maligno

Palabras clave

Checkpoint inhibitor; Melanoma; Survival; Tumor microenvironment; Tumor-infiltrating lymphocytes; VISTA

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Biomarcadores de Tumor / Linfocitos Infiltrantes de Tumor / Antígenos B7 / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 / Melanoma Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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