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Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis.
McKenzie, Brienne A; Mamik, Manmeet K; Saito, Leina B; Boghozian, Roobina; Monaco, Maria Chiara; Major, Eugene O; Lu, Jian-Qiang; Branton, William G; Power, Christopher.
Afiliación
  • McKenzie BA; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Mamik MK; Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Saito LB; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Boghozian R; Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Monaco MC; Department of Immunology, Tehran University of Medical Sciences, Tehran 1417653761, Iran.
  • Major EO; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Lu JQ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
  • Branton WG; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Power C; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Proc Natl Acad Sci U S A ; 115(26): E6065-E6074, 2018 06 26.
Article en En | MEDLINE | ID: mdl-29895691
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligodendroglía / Caspasa 1 / Dipéptidos / Para-Aminobenzoatos / Inhibidores de Caspasas / Piroptosis / Modelos Biológicos / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Canadá
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligodendroglía / Caspasa 1 / Dipéptidos / Para-Aminobenzoatos / Inhibidores de Caspasas / Piroptosis / Modelos Biológicos / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Canadá