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The dual inhibitor of the phosphoinositol-3 and PIM kinases, IBL-202, is effective against chronic lymphocytic leukaemia cells under conditions that mimic the hypoxic tumour microenvironment.
Crassini, Kyle; Shen, Yandong; O'Dwyer, Michael; O'Neill, Michael; Christopherson, Richard; Mulligan, Stephen; Best, O Giles.
Afiliación
  • Crassini K; Northern Blood Research Centre, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, Sydney, Australia.
  • Shen Y; Northern Blood Research Centre, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, Sydney, Australia.
  • O'Dwyer M; School of Molecular Biosciences, University of Sydney, Sydney, Australia.
  • O'Neill M; National University of Galway, Galway, Ireland.
  • Christopherson R; Inflection Biosciences Ltd, Dublin, Ireland.
  • Mulligan S; School of Molecular Biosciences, University of Sydney, Sydney, Australia.
  • Best OG; Northern Blood Research Centre, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, Sydney, Australia.
Br J Haematol ; 182(5): 654-669, 2018 09.
Article en En | MEDLINE | ID: mdl-29978459
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Linfocítica Crónica de Células B / Inhibidores de Proteínas Quinasas Límite: Humans Idioma: En Revista: Br J Haematol Año: 2018 Tipo del documento: Article País de afiliación: Australia
Texto completo
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XML
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Linfocítica Crónica de Células B / Inhibidores de Proteínas Quinasas Límite: Humans Idioma: En Revista: Br J Haematol Año: 2018 Tipo del documento: Article País de afiliación: Australia