Synthesis of substituted 2<i>H</i>-benzo[<i>e</i>]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3ß pathways.

Taneja, Gaurav; Gupta, Chandra Prakash; Mishra, Shachi; Srivastava, Rohit; Rahuja, Neha; Rawat, Arun Kumar; Pandey, Jyotsana; Gupta, Anand P; Jaiswal, Natasha; Gayen, Jiaur R; Tamrakar, Akhilesh K; Srivastava, Arvind Kumar; Goel, Atul

Synthesis of substituted 2H-benzo[e]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3ß pathways.

Taneja, Gaurav; Gupta, Chandra Prakash; Mishra, Shachi; Srivastava, Rohit; Rahuja, Neha; Rawat, Arun Kumar; Pandey, Jyotsana; Gupta, Anand P; Jaiswal, Natasha; Gayen, Jiaur R; Tamrakar, Akhilesh K; Srivastava, Arvind Kumar; Goel, Atul.

Afiliación

Taneja G; Medicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India . Email: atul_goel@cdri.res.in.
Gupta CP; Medicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India . Email: atul_goel@cdri.res.in.
Mishra S; Medicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India . Email: atul_goel@cdri.res.in.
Srivastava R; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Rahuja N; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Rawat AK; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Pandey J; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Gupta AP; Pharmacokinetics and Metabolism Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Jaiswal N; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Gayen JR; Pharmacokinetics and Metabolism Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Tamrakar AK; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Srivastava AK; Biochemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
Goel A; Medicinal and Process Chemistry Division , CSIR-Central Drug Research Institute , Lucknow 226031 , India . Email: atul_goel@cdri.res.in.

Medchemcomm ; 8(2): 329-337, 2017 Feb 01.

Article en En | MEDLINE | ID: mdl-30108748

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Medchemcomm Año: 2017 Tipo del documento: Article

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Medchemcomm Año: 2017 Tipo del documento: Article