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Quiescent Endothelial Cells Upregulate Fatty Acid ß-Oxidation for Vasculoprotection via Redox Homeostasis.
Kalucka, Joanna; Bierhansl, Laura; Conchinha, Nadine Vasconcelos; Missiaen, Rindert; Elia, Ilaria; Brüning, Ulrike; Scheinok, Samantha; Treps, Lucas; Cantelmo, Anna Rita; Dubois, Charlotte; de Zeeuw, Pauline; Goveia, Jermaine; Zecchin, Annalisa; Taverna, Federico; Morales-Rodriguez, Francisco; Brajic, Aleksandra; Conradi, Lena-Christin; Schoors, Sandra; Harjes, Ulrike; Vriens, Kim; Pilz, Gregor-Alexander; Chen, Rongyuan; Cubbon, Richard; Thienpont, Bernard; Cruys, Bert; Wong, Brian W; Ghesquière, Bart; Dewerchin, Mieke; De Bock, Katrien; Sagaert, Xavier; Jessberger, Sebastian; Jones, Elizabeth A V; Gallez, Bernard; Lambrechts, Diether; Mazzone, Massimiliano; Eelen, Guy; Li, Xuri; Fendt, Sarah-Maria; Carmeliet, Peter.
Afiliación
  • Kalucka J; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 51006, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism,
  • Bierhansl L; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Conchinha NV; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Missiaen R; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Elia I; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium
  • Brüning U; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Scheinok S; Université Catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, 1200 Brussels, Belgium.
  • Treps L; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Cantelmo AR; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Dubois C; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • de Zeeuw P; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Goveia J; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Zecchin A; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Taverna F; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Morales-Rodriguez F; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Brajic A; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Conradi LC; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Schoors S; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Harjes U; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Vriens K; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium
  • Pilz GA; Brain Research Institute, Faculty of Medicine and Science, University of Zurich, Zurich 8057, Switzerland.
  • Chen R; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 51006, Guangdong, P.R. China.
  • Cubbon R; Division of Cardiovascular and Diabetes Research, Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds LS2 9JT, UK.
  • Thienpont B; Laboratory of Translational Genetics, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium; Laboratory of Translational Genetics, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium.
  • Cruys B; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Wong BW; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Ghesquière B; Metabolomics Expertise Center, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Metabolomics Expertise Center, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.
  • Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • De Bock K; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Sagaert X; Translational Cell & Tissue Research, Department of Imaging & Pathology, KU Leuven, 3000 Leuven, Belgium.
  • Jessberger S; Brain Research Institute, Faculty of Medicine and Science, University of Zurich, Zurich 8057, Switzerland.
  • Jones EAV; Department of Cardiovascular Sciences, KU Leuven, UZ Herestraat 49, Box 911, 3000 Leuven, Belgium; Centre for Molecular and Vascular Biology, KU Leuven, UZ Herestraat 49, Box 911, 3000 Leuven, Belgium.
  • Gallez B; Université Catholique de Louvain, Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, 1200 Brussels, Belgium.
  • Lambrechts D; Laboratory of Translational Genetics, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium; Laboratory of Translational Genetics, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium.
  • Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, University of Leuven, 3000 Leuven, Belgium.
  • Eelen G; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium.
  • Li X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 51006, Guangdong, P.R. China. Electronic address: lixr6@mail.sysu.edu.cn.
  • Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium
  • Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 51006, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism,
Cell Metab ; 28(6): 881-894.e13, 2018 12 04.
Article en En | MEDLINE | ID: mdl-30146488
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carnitina O-Palmitoiltransferasa / Metabolismo Energético / Receptor Notch1 / Ácidos Grasos / Células Endoteliales de la Vena Umbilical Humana / NADP Límite: Animals / Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carnitina O-Palmitoiltransferasa / Metabolismo Energético / Receptor Notch1 / Ácidos Grasos / Células Endoteliales de la Vena Umbilical Humana / NADP Límite: Animals / Humans Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2018 Tipo del documento: Article