Hypermethylation of miR-338-3p and Impact of its Suppression on Cell Metastasis Through N-Cadherin Accumulation at the Cell -Cell Junction and Degradation of MMP in Gastric Cancer.

Guo, Bo; Zhang, Jing; Li, Qian; Zhao, Zhenghao; Wang, Wenjing; Zhou, Kaiyue; Wang, Xiaofei; Tong, Dongdong; Zhao, Lingyu; Yang, Juan; Huang, Chen

Guo, Bo; Zhang, Jing; Li, Qian; Zhao, Zhenghao; Wang, Wenjing; Zhou, Kaiyue; Wang, Xiaofei; Tong, Dongdong; Zhao, Lingyu; Yang, Juan; Huang, Chen.

Afiliación

Guo B; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi An, China.
Zhang J; Department of Clinical Medicine, Medical College of Yan'an University, Yan'an, China.
Li Q; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi An, China.
Zhao Z; The ART Center, Northwest Women's and Children's Hospital, Xi An, China.
Wang W; Department of Hepatobiliary Surgery, First Affiliated Hospital, Xi'an Jiaotong University, Xi An, China.
Zhou K; Program in Plant Biology and Conservation, Biological Sciences, Weinberg College of Arts and Sciences, Northwestern University, Evanston, Illinois, USA.
Wang X; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong University, Ministry of Education of China, Xi An, China.
Tong D; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi An, China.
Zhao L; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi An, China.
Yang J; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi An, China.
Huang C; Department of Cell Biology and Genetics, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi An, China.

Cell Physiol Biochem ; 50(2): 411-425, 2018.

Article en En | MEDLINE | ID: mdl-30308487

Asunto(s)

Cadherinas/metabolismo; Uniones Intercelulares/metabolismo; Metaloproteinasas de la Matriz/metabolismo; MicroARNs/metabolismo; Neoplasias Gástricas/patología; Regiones no Traducidas 3'; Aciltransferasas/antagonistas & inhibidores; Aciltransferasas/genética; Aciltransferasas/metabolismo; Antagomirs/metabolismo; Secuencia de Bases; Línea Celular Tumoral; Movimiento Celular; Metilación de ADN; Humanos; MicroARNs/antagonistas & inhibidores; MicroARNs/genética; Interferencia de ARN; ARN Interferente Pequeño/metabolismo; Alineación de Secuencia; Transducción de Señal; Neoplasias Gástricas/genética; Proteínas de Unión al GTP rab/antagonistas & inhibidores; Proteínas de Unión al GTP rab/genética; Proteínas de Unión al GTP rab/metabolismo

Palabras clave

Gastric cancer; Hhat-MMP signaling; Metastasis; Rab14-N-cadherin; miR-338-3p

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Cadherinas / Metaloproteinasas de la Matriz / MicroARNs / Uniones Intercelulares Límite: Humans Idioma: En Revista: Cell Physiol Biochem Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China

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