Regulation of capillary tubules and lipid formation in vascular endothelial cells and macrophages via extracellular vesicle-mediated microRNA-4306 transfer.

Yang, Ying; Luo, Hui; Zhou, Can; Zhang, Rongyi; Liu, Si; Zhu, Xiao; Ke, Sha; Liu, Hui; Lu, Zhan; Chen, Mao

Yang, Ying; Luo, Hui; Zhou, Can; Zhang, Rongyi; Liu, Si; Zhu, Xiao; Ke, Sha; Liu, Hui; Lu, Zhan; Chen, Mao.

Afiliación

Yang Y; 1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Luo H; 2 Department of Cardiothoracic Surgery, Nanchong Central Hospital, Nanchong, China.
Zhou C; 1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Zhang R; 3 Department of Cardiology, Nanchong Central Hospital, Nanchong, China.
Liu S; 3 Department of Cardiology, Nanchong Central Hospital, Nanchong, China.
Zhu X; 1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Ke S; 1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Liu H; 1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Lu Z; 1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, China; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Chen M; 4 Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China.

J Int Med Res ; 47(1): 453-469, 2019 Jan.

Article en En | MEDLINE | ID: mdl-30477383

Asunto(s)

Enfermedad de la Arteria Coronaria/metabolismo; Células Endoteliales/metabolismo; Vesículas Extracelulares/metabolismo; Macrófagos/metabolismo; MicroARNs/genética; Antagomirs/genética; Antagomirs/metabolismo; Estudios de Casos y Controles; Movimiento Celular; Proliferación Celular; Angiografía Coronaria; Enfermedad de la Arteria Coronaria/diagnóstico por imagen; Enfermedad de la Arteria Coronaria/genética; Enfermedad de la Arteria Coronaria/cirugía; Células Endoteliales/efectos de los fármacos; Células Endoteliales/patología; Vesículas Extracelulares/química; Regulación de la Expresión Génica; Genes Reporteros; Humanos; Lipoproteínas LDL/farmacología; Luciferasas/genética; Luciferasas/metabolismo; Macrófagos/efectos de los fármacos; Macrófagos/patología; MicroARNs/agonistas; MicroARNs/antagonistas & inhibidores; MicroARNs/metabolismo; FN-kappa B/genética; FN-kappa B/metabolismo; Oligorribonucleótidos/genética; Oligorribonucleótidos/metabolismo; Comunicación Paracrina; Intervención Coronaria Percutánea; Cultivo Primario de Células; Proteínas Proto-Oncogénicas c-akt/genética; Proteínas Proto-Oncogénicas c-akt/metabolismo; Transducción de Señal

Palabras clave

Extracellular vesicle; coronary artery disease; human coronary artery vascular endothelial cell; human monocyte-derived macrophage; lipid; miR-4306; oxidized low-density lipoprotein

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / MicroARNs / Células Endoteliales / Vesículas Extracelulares / Macrófagos Tipo de estudio: Observational_studies Idioma: En Revista: J Int Med Res Año: 2019 Tipo del documento: Article País de afiliación: China

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