Reception of Sex Steroid Hormones in Thyroid Papillary Cancer Tissue and Relationship with Expression and Content of Transcription Factors Brn-3α and TRIM16.
Bull Exp Biol Med
; 166(2): 237-240, 2018 Dec.
Article
en En
| MEDLINE
| ID: mdl-30488195
We studied reception of sex steroid hormones in the tissues of thyroid papillary cancer and benign tumor. Enhanced expression of AR and ERß mRNA reflected malignant tumor growth. Nuclear factors Brn-3α and TRIM16 modulating expression of steroid hormones play an important role in the development of thyroid tumors. It was found that the level of TRIM16 mRNA is associated with the expression of ERß, which seems to be mediated by its antiestrogen effect.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Factores de Transcripción
/
Neoplasias de la Tiroides
/
Receptores Androgénicos
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Regulación Neoplásica de la Expresión Génica
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Receptor beta de Estrógeno
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Proteínas de Unión al ADN
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Factor de Transcripción Brn-3A
/
Cáncer Papilar Tiroideo
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Bull Exp Biol Med
Año:
2018
Tipo del documento:
Article
País de afiliación:
Rusia