Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.

Zhang, Ke; Shang, Guijun; Padavannil, Abhilash; Wang, Juan; Sakthivel, Ramanavelan; Chen, Xiang; Kim, Min; Thompson, Matthew G; García-Sastre, Adolfo; Lynch, Kristen W; Chen, Zhijian J; Chook, Yuh Min; Fontoura, Beatriz M A

Zhang, Ke; Shang, Guijun; Padavannil, Abhilash; Wang, Juan; Sakthivel, Ramanavelan; Chen, Xiang; Kim, Min; Thompson, Matthew G; García-Sastre, Adolfo; Lynch, Kristen W; Chen, Zhijian J; Chook, Yuh Min; Fontoura, Beatriz M A.

Afiliación

Zhang K; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Shang G; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Padavannil A; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Wang J; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Sakthivel R; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Chen X; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Kim M; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Thompson MG; Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
García-Sastre A; Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.
Lynch KW; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Chen ZJ; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Chook YM; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029.
Fontoura BMA; Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.

Proc Natl Acad Sci U S A ; 115(52): E12218-E12227, 2018 12 26.

Article en En | MEDLINE | ID: mdl-30538201

Asunto(s)

Virus de la Influenza A/metabolismo; Gripe Humana/metabolismo; Proteínas Nucleares/química; Proteínas Nucleares/metabolismo; ARN Mensajero/genética; Factores de Transcripción/química; Factores de Transcripción/metabolismo; Transporte Activo de Núcleo Celular; Núcleo Celular/genética; Núcleo Celular/metabolismo; Cristalografía por Rayos X; Dimerización; Ribonucleoproteínas Nucleares Heterogéneas/genética; Ribonucleoproteínas Nucleares Heterogéneas/metabolismo; Humanos; Virus de la Influenza A/química; Virus de la Influenza A/genética; Gripe Humana/genética; Gripe Humana/virología; Proteínas Nucleares/genética; Proteína de Unión al Tracto de Polipirimidina/genética; Proteína de Unión al Tracto de Polipirimidina/metabolismo; Unión Proteica; Dominios Proteicos; Empalme del ARN; ARN Mensajero/metabolismo; Proteínas de Unión al ARN; Factores de Transcripción/genética; Proteínas no Estructurales Virales/genética; Proteínas no Estructurales Virales/metabolismo

Palabras clave

Kelch; NS1 protein; influenza virus; mRNA export; splicing

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus de la Influenza A / Factores de Transcripción / ARN Mensajero / Proteínas Nucleares / Gripe Humana Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article

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