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Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12.
Garris, Christopher S; Arlauckas, Sean P; Kohler, Rainer H; Trefny, Marcel P; Garren, Seth; Piot, Cécile; Engblom, Camilla; Pfirschke, Christina; Siwicki, Marie; Gungabeesoon, Jeremy; Freeman, Gordon J; Warren, Sarah E; Ong, SuFey; Browning, Erica; Twitty, Christopher G; Pierce, Robert H; Le, Mai H; Algazi, Alain P; Daud, Adil I; Pai, Sara I; Zippelius, Alfred; Weissleder, Ralph; Pittet, Mikael J.
Afiliación
  • Garris CS; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA; Graduate Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Arlauckas SP; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA; Department of Radiology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Kohler RH; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Trefny MP; Medical Oncology, Universitätsspital Basel, Basel, Switzerland; Cancer Immunology, Department of Biomedicine and Medical Oncology, University Hospital Basel, Switzerland.
  • Garren S; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Piot C; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Engblom C; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Pfirschke C; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Siwicki M; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA; Graduate Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.
  • Gungabeesoon J; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA.
  • Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
  • Warren SE; NanoString Technologies, 500 Fairview Ave N, Seattle, WA 98109, USA.
  • Ong S; NanoString Technologies, 500 Fairview Ave N, Seattle, WA 98109, USA.
  • Browning E; Oncosec Inc, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Twitty CG; Oncosec Inc, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Pierce RH; Oncosec Inc, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Le MH; Oncosec Inc, 5820 Nancy Ridge Drive, San Diego, CA 92121, USA.
  • Algazi AP; University of California, San Francisco Medical Center-Mt. Zion, 1600 Divisadero St, San Francisco, CA 94115, USA.
  • Daud AI; University of California, San Francisco Medical Center-Mt. Zion, 1600 Divisadero St, San Francisco, CA 94115, USA.
  • Pai SI; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Zippelius A; Medical Oncology, Universitätsspital Basel, Basel, Switzerland.
  • Weissleder R; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA; Department of Radiology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA; Department of Systems Biology, Harvard Medical School, 200 Longwood Ave, Boston
  • Pittet MJ; Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA; Department of Radiology, Massachusetts General Hospital, 185 Cambridge St, CPZN 5206, Boston, MA 02114, USA. Electronic address: mpittet@mgh.harvard.edu.
Immunity ; 49(6): 1148-1161.e7, 2018 12 18.
Article en En | MEDLINE | ID: mdl-30552023
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Dendríticas / Linfocitos T / Interferón gamma / Interleucina-12 / Receptor de Muerte Celular Programada 1 / Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Dendríticas / Linfocitos T / Interferón gamma / Interleucina-12 / Receptor de Muerte Celular Programada 1 / Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos