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SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis.
Wang, Guihua; Long, Jie; Gao, Yuan; Zhang, Weina; Han, Fei; Xu, Chuan; Sun, Li; Yang, Shun-Chin; Lan, Jingqin; Hou, Zhenlin; Cai, Zhen; Jin, Guoxiang; Hsu, Che-Chia; Wang, Yu-Hui; Hu, Junbo; Chen, Tsai-Yu; Li, Hongyu; Lee, Min Gyu; Lin, Hui-Kuan.
Afiliación
  • Wang G; Department of GI Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Long J; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Gao Y; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Zhang W; Department of Pathology, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Han F; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Xu C; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Sun L; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Yang SC; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Lan J; Department of GI Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Hou Z; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Cai Z; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Jin G; Department of GI Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Hsu CC; Department of GI Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Wang YH; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Hu J; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Chen TY; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Li H; Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, NC, USA.
  • Lee MG; Department of GI Cancer Research Institute, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Lin HK; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nat Cell Biol ; 21(2): 214-225, 2019 02.
Article en En | MEDLINE | ID: mdl-30692626
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Metiltransferasas / Proteínas Proto-Oncogénicas c-akt / Ubiquitinación / Carcinogénesis Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Cell Biol Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína Metiltransferasas / Proteínas Proto-Oncogénicas c-akt / Ubiquitinación / Carcinogénesis Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Cell Biol Año: 2019 Tipo del documento: Article País de afiliación: China