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Histone modifications underlie monocyte dysregulation in patients with systemic sclerosis, underlining the treatment potential of epigenetic targeting.
van der Kroef, Maarten; Castellucci, Monica; Mokry, Michal; Cossu, Marta; Garonzi, Marianna; Bossini-Castillo, Lara M; Chouri, Eleni; Wichers, Catharina G K; Beretta, Lorenzo; Trombetta, Elena; Silva-Cardoso, Sandra; Vazirpanah, Nadia; Carvalheiro, Tiago; Angiolilli, Chiara; Bekker, Cornelis P J; Affandi, Alsya J; Reedquist, Kris A; Bonte-Mineur, Femke; Zirkzee, Els J M; Bazzoni, Flavia; Radstake, Timothy R D J; Rossato, Marzia.
Afiliación
  • van der Kroef M; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Castellucci M; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Mokry M; Division of General Pathology, Department of Medicine, University of Verona, Verona, Italy.
  • Cossu M; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Garonzi M; Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Bossini-Castillo LM; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Chouri E; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Wichers CGK; Department of Biotechnology, University of Verona, Verona, Italy.
  • Beretta L; Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), Instituto de Parasitología y Biomedicina López-Neyra, PTS Granada, Granada, Spain.
  • Trombetta E; Department of cellular genetics, Wellcome Trust Sanger Institute, Cambridge, UK.
  • Silva-Cardoso S; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Vazirpanah N; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Carvalheiro T; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Angiolilli C; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Bekker CPJ; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
  • Affandi AJ; Flow Cytometry Service, Analysis Laboratory, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.
  • Reedquist KA; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Bonte-Mineur F; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Zirkzee EJM; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Bazzoni F; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Radstake TRDJ; Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Rossato M; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Ann Rheum Dis ; 78(4): 529-538, 2019 04.
Article en En | MEDLINE | ID: mdl-30793699
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Esclerodermia Sistémica / Monocitos / Epigénesis Genética / Código de Histonas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Esclerodermia Sistémica / Monocitos / Epigénesis Genética / Código de Histonas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos