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Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.
Grootjans, Joep; Krupka, Niklas; Hosomi, Shuhei; Matute, Juan D; Hanley, Thomas; Saveljeva, Svetlana; Gensollen, Thomas; Heijmans, Jarom; Li, Hai; Limenitakis, Julien P; Ganal-Vonarburg, Stephanie C; Suo, Shengbao; Luoma, Adrienne M; Shimodaira, Yosuke; Duan, Jinzhi; Shih, David Q; Conner, Margaret E; Glickman, Jonathan N; Fuhler, Gwenny M; Palm, Noah W; de Zoete, Marcel R; van der Woude, C Janneke; Yuan, Guo-Cheng; Wucherpfennig, Kai W; Targan, Stephan R; Rosenstiel, Philip; Flavell, Richard A; McCoy, Kathy D; Macpherson, Andrew J; Kaser, Arthur; Blumberg, Richard S.
Afiliación
  • Grootjans J; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Krupka N; Amsterdam University Medical Center, University of Amsterdam, Department of Gastroenterology and Hepatology and Tygat Institute for Liver and Intestinal Research, Meibergdreef 9, Amsterdam, Netherlands.
  • Hosomi S; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Matute JD; Maurice Müller Laboratories (DBMR), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3010 Bern, Switzerland.
  • Hanley T; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Saveljeva S; Department of Gastroenterology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
  • Gensollen T; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Heijmans J; Division of Neonatology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Li H; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Limenitakis JP; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
  • Ganal-Vonarburg SC; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Suo S; Amsterdam University Medical Center, University of Amsterdam, Department of Internal Medicine, Tygat Institute for Liver and Intestinal Research, Meibergdreef 9, Amsterdam, Netherlands.
  • Luoma AM; Maurice Müller Laboratories (DBMR), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3010 Bern, Switzerland.
  • Shimodaira Y; Maurice Müller Laboratories (DBMR), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3010 Bern, Switzerland.
  • Duan J; Maurice Müller Laboratories (DBMR), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3010 Bern, Switzerland.
  • Shih DQ; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Conner ME; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • Glickman JN; F. Widjaja Foundation, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Fuhler GM; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
  • Palm NW; F. Widjaja Foundation, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • de Zoete MR; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
  • van der Woude CJ; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Yuan GC; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
  • Wucherpfennig KW; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
  • Targan SR; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.
  • Rosenstiel P; Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
  • Flavell RA; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • McCoy KD; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.
  • Macpherson AJ; F. Widjaja Foundation, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Kaser A; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany.
  • Blumberg RS; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Science ; 363(6430): 993-998, 2019 03 01.
Article en En | MEDLINE | ID: mdl-30819965
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoglobulina A / Inmunidad Mucosa / Células Epiteliales / Estrés del Retículo Endoplásmico / Mucosa Intestinal Límite: Animals / Humans Idioma: En Revista: Science Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoglobulina A / Inmunidad Mucosa / Células Epiteliales / Estrés del Retículo Endoplásmico / Mucosa Intestinal Límite: Animals / Humans Idioma: En Revista: Science Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos