UCP2 ameliorates mitochondrial dysfunction, inflammation, and oxidative stress in lipopolysaccharide-induced acute kidney injury.

Ding, Yue; Zheng, Yijun; Huang, Jinda; Peng, Wanwan; Chen, Xinxin; Kang, Xiangjin; Zeng, Qiyi

Ding, Yue; Zheng, Yijun; Huang, Jinda; Peng, Wanwan; Chen, Xinxin; Kang, Xiangjin; Zeng, Qiyi.

Afiliación

Ding Y; Department of Pediatrics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510280, Guangdong, China.
Zheng Y; Department of Pediatrics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510280, Guangdong, China.
Huang J; Department of Pediatrics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510280, Guangdong, China.
Peng W; Department of Pediatrics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510280, Guangdong, China.
Chen X; Department of Pediatrics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510280, Guangdong, China.
Kang X; Center for Reproductive Medicine, Third Affiliated Hospital of Guangzhou Medical University; Key Laboratory for Reproductive Medicine of Guangdong Province; Key Laboratory for Major Obstetric Diseases of Guangdong Province; Key Laboratory of Reproduction and Genetics of Guangdong Higher Education In
Zeng Q; Department of Pediatrics, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510280, Guangdong, China. Electronic address: zqy_88@163.com.

Int Immunopharmacol ; 71: 336-349, 2019 Jun.

Article en En | MEDLINE | ID: mdl-30952098

Asunto(s)

Lesión Renal Aguda/metabolismo; Túbulos Renales/patología; Mitocondrias/metabolismo; Sepsis/metabolismo; Proteína Desacopladora 2/metabolismo; Urotelio/metabolismo; Animales; Línea Celular; Modelos Animales de Enfermedad; Humanos; Inflamación; Lipopolisacáridos/inmunología; Masculino; Ratones; Ratones Endogámicos C57BL; Mitocondrias/patología; Estrés Oxidativo; ARN Interferente Pequeño/genética; Proteína Desacopladora 2/genética; Urotelio/patología

Palabras clave

Acute kidney injury; Inflammation; LPS; Mitochondrial; Oxidative stress; Uncoupling protein 2

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sepsis / Urotelio / Lesión Renal Aguda / Proteína Desacopladora 2 / Túbulos Renales / Mitocondrias Límite: Animals / Humans / Male Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: China

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