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Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu, Zhenlong; Jv, Yanan; Cai, Lu; Tian, Xiangge; Huo, Xiaokui; Wang, Chao; Zhang, Baojing; Sun, ChengPeng; Ning, Jing; Feng, Lei; Zhang, Houli; Ma, Xiaochi.
Afiliación
  • Yu Z; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Jv Y; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Cai L; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Tian X; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Huo X; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Wang C; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Zhang B; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Sun C; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Ning J; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Feng L; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China.
  • Zhang H; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China. Electronic address: zhanghouli@dmu.edu.cn.
  • Ma X; College of Pharmacy, Academy of Integrative Medicine, Dalian Medical University, Dalian 116044, China. Electronic address: maxc1978@163.com.
Toxicol Appl Pharmacol ; 371: 63-73, 2019 05 15.
Article en En | MEDLINE | ID: mdl-30953615
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas HSP90 de Choque Térmico / Proteínas Quinasas Activadas por Mitógenos / Xantonas / Proteínas Proto-Oncogénicas c-akt / Células Estrelladas Hepáticas / Fosfatidilinositol 3-Quinasa / Hígado / Cirrosis Hepática Experimental Límite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas HSP90 de Choque Térmico / Proteínas Quinasas Activadas por Mitógenos / Xantonas / Proteínas Proto-Oncogénicas c-akt / Células Estrelladas Hepáticas / Fosfatidilinositol 3-Quinasa / Hígado / Cirrosis Hepática Experimental Límite: Animals / Humans / Male Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China